TB-500 (Thymosin Beta-4 Fragment)

$49.00

Synthetic actin-binding peptide fragment · Research Use Only

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Research Use Only.

This compound is supplied strictly for in vitro research purposes. It is not approved by the FDA and is not intended for human consumption, therapeutic, diagnostic, or veterinary use. By purchasing, you confirm you are a qualified researcher aged 18+.

Description

TB-500 is a synthetic analog of the naturally occurring 43-amino-acid protein Thymosin Beta-4, representing the active fragment (residues 17–23) studied for its bioactivity and stability in laboratory settings.

Research focus: Research centers on TB-500’s actin-sequestering activity — it binds monomeric G-actin, which in preclinical models enables rapid cytoskeletal remodeling relevant to cell migration during tissue repair. Studies have reported increased VEGF expression (angiogenesis), accelerated wound closure in diabetic animal models, reduced infarct size in cardiac models, and increased tensile strength in tendon-repair models.

Specifications

Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln

Molecular formula: C₃₉H₆₇N₉O₁₃

Molecular weight: ~877.99 g/mol

CAS: 885340-08-9

Purity: ≥99% (HPLC verified)

Form: Lyophilized powder

For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, or consumption. Not evaluated by the FDA.

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